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Although the medicine for sleep disorders is already booming, terms obstructive sleep apnea are still foreign in the ears of the public. The disease is rarely detected, even by doctors. OSA is still often under-diagnosed and when left, OSA can cause various complications of cardiovascular, nervous disorders, metabolic syndrome, and hormone balance.
Of the many complications that may be caused by this disease, there are three serious diseases we need to beware of. Three of these diseases have a lifetime of treatment impact can also be life threatening, so we should not again underestimate the habitual snoring. What are the 3 of the disease? Yuk, follow the following explanation.
1. HYPERTENSION and STROKE POTENTIAL
In the case of obstructive sleep apnea (OSA), over 50% of patients experience complications of hypertension or high blood pressure. This is due to decreased levels of oxygen that makes the body secretes a variety of compounds. One of these Catecholamines. Catecholamines will make the flexibility of blood vessels become diminished, so tend to be narrowed. In addition, the State of the lack of oxygen (hypoxia) also stimulates the nervous system an increasingly sympathetic dystrophy narrowed its blood vessels while increasing heart rate.
Initially, the increased blood pressure can still be overcome. However, if it is continued in the long term, the combination of high levels of Catecholamines and sympathetic dystrophy nerve activity became the forerunner to hypertension in people with OSA. Repeated blood pressure changes due to changes in breathing patterns during sleep in OSA can make pressure sensor reflex (baroreseptor) will be decreased. This causes the central pressure sensor it becomes less sensitive, which ended with an increase in blood pressure continuously.
Hypertension that occurs in patients who did not receive or Undiagnosed OSA OSA treatment is good, it becomes difficult to overcome and triggering further complications, such as bleeding stroke. Treatment of OSA are effective will fix the terkontrolnya blood pressure in many patients.
2. DIABETES MELLITUS TYPE 2 (DM type 2)
Approximately 40% of patients will experience an OSA type 2 diabetes, and type 2 diabetes patients have the possibility of suffering from OSA to 23%. So, there is a reciprocal relationship between OSA and diabetes type 2. There are several reasons why OSA can lead to diabetes mellitus, namely:
- Sympathetic dystrophy nervous system hold a major role in setting the metabolism of glucose and fat. In people with OSA, the nervous system is aroused so the chaos that causes blood glucose levels become high.
- The State of the lack of oxygen (hypoxia) in people with OSA can decrease insulin sensitivity and glucose tolerance, thus exacerbating the glucose present in the blood cannot enter the network and utilized as fuel for energy.
- Hypoxia and sleep disorders cause a hormonal imbalance that is increased levels of cortisol with a pattern of abnormal and excessive. These hormones inhibit the sensitivity level of the hormone insulin which regulates blood glucose levels
A study mentioned that treatment of OSA with diabetes be complex because there are drug interactions that cause diabetes medication dosage decreased, so that early detection and treatment must be carried out more aggressive.
3. CORONARY HEART DISEASE
Study on animal experiments indicate lack of oxygen led to chaos on the genes that produce fat on liver metabolism disorders occur, so the fat. These conditions depend on the severity of hypoxia. Low blood oxygen levels in people with OSA causes a 30% increase in fat components such as triglycerides. So, on the condition of the OSA customarily found increased levels of evil fat (LDL cholesterol) and a decrease in good fats (HDL cholesterol). This triggered an increase in the formation of the crust in the blood vessels of the body.
Effects of lack of oxygen also causes oxygen flow to the heart is reduced. This causes the heart muscle doesn't get the blood pumping to the maximum to other organs. The combination of jeleknya profile of fat and oxygen flow barriers can cause the heart muscle to die of a heart attack, so that it can not be inevitable.
Well, that's 3 a serious disease that can occur due to ngorok. Therefore, remind yourself also loved ones to immediately to the doctor, when shows symptoms of snoring that is unnatural. Do not let this disease came went in first.
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